Reaction: FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP
Addition of a fucose moiety as an alpha 1-6 linkage to the first GlcNAc residue of the N-glycan (Clarke JL, Watkins WM 1999; Yamaguchi Y et al, 1999; Yamaguchi Y et al 2000).
Reaction - small molecule participants:
GDP [Golgi lumen]
NGP [Golgi lumen]
GDP-Fuc [Golgi lumen]
Reactome.org reaction link: R-HSA-1028788
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Reaction input - small molecules:
N-glycan
GDP-L-fucose
Reaction output - small molecules:
GDP(3-)
Reactome.org link: R-HSA-1028788