Reaction: Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation
Three cycles of beta oxidation, each mediated by the activities of trifunctional protein and ACADL tetramer, convert linoleoyl-CoA to cis,cis-3,6-dodecadienoyl-CoA plus three molecules each of CoA-SH, FADH2, and NADH + H+.
Reaction - small molecule participants:
cis,cis-3,6-Dodecadienoyl-CoA [mitochondrial matrix]
H+ [mitochondrial matrix]
Ac-CoA [mitochondrial matrix]
NADH [mitochondrial matrix]
FADH2 [mitochondrial matrix]
CoA-SH [mitochondrial matrix]
LIN-CoA [mitochondrial matrix]
FAD [mitochondrial matrix]
NAD+ [mitochondrial matrix]
H2O [mitochondrial matrix]
Reactome.org reaction link: R-HSA-109339
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Reaction input - small molecules:
coenzyme A(4-)
linoleoyl-CoA
FAD(3-)
NAD(1-)
water
Reaction output - small molecules:
(3Z,6Z)-dodecadienoyl-CoA
hydron
acetyl-CoA(4-)
NADH(2-)
FADH2(2-)
Reactome.org link: R-HSA-109339