Reaction: AMP + ATP <=> ADP + ADP [AK2]
- in pathway: Interconversion of nucleotide di- and triphosphates
Mitochondrial adenylate kinase 2 (AK2) catalyzes the reaction of AMP and ATP to form two molecules of ADP (Hamade et al. 1982). Localization of AK2 specifically to the mitochondrial intermembrane space is inferred from studies of the homologous rat enzyme (Criss 1970).
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
AMP [cytosol]
Reactome.org reaction link: R-HSA-110145
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Reaction input - small molecules:
ATP(4-)
adenosine 5'-monophosphate(2-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-110145