Reaction: Cleavage of ethenocytosine by TDG glycosylase
- in pathway: Cleavage of the damaged pyrimidine
TDG, a G/T mismatch-specific DNA glycosylase, cleaves ethenocytosine mispaired with guanine, leaving an apurinic/apyrimidinic (AP) site in the DNA (Hang et al. 1998).
Reaction - small molecule participants:
EtCYT [nucleoplasm]
Reactome.org reaction link: R-HSA-110234
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Reaction input - small molecules:
Reaction output - small molecules:
3,N(4)-ethenocytosine
Reactome.org link: R-HSA-110234