Reaction: Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break
After incision of the DNA strand 5' to the apurinic/apyrimidinic (AP) site by APEX1 (APE1), POLB (DNA polymerase beta) excises the 5'-terminal abasic deoxyribose phosphate (5'-dRP), thus removing the AP site (Bennet et al. 1997).
Reaction - small molecule participants:
SUGP [nucleoplasm]
Reactome.org reaction link: R-HSA-110375
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Reaction input - small molecules:
Reaction output - small molecules:
phospho sugar
Reactome.org link: R-HSA-110375