Reaction: Adenylate cyclase produces cAMP
- in pathway: PKA activation
Adenylate cyclase is responsive to calcium and calmodulin and produces cAMP. One important physiological role for Calmodulin is the regulation of adenylylcyclases. Four of the ten known adenylylcyclases are calcium sensitive, in particular type 8 (AC8).
Reaction - small molecule participants:
PPi [cytosol]
cAMP [cytosol]
ATP [cytosol]
PPi [cytosol]
cAMP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-111930
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Reaction input - small molecules:
ATP(4-)
ATP(4-)
Reaction output - small molecules:
diphosphate(3-)
3',5'-cyclic AMP(1-)
diphosphate(3-)
3',5'-cyclic AMP(1-)
Reactome.org link: R-HSA-111930