Reaction: Carboxymycobactin and mycobactin exchange their iron load
- in pathway: Mtb iron assimilation by chelation
Carboxymycobactin and mycobactin exchange their iron loads. This interplay between polar and nonpolar siderophore is unique to Mtb. However, mycobactin can gather iron from nonpolar regions of the host cell by itself too (Madigan et al. 2012).
Reaction - small molecule participants:
Carboxymycobactin [phagocytic vesicle lumen]
Mycobactin [peptidoglycan-based cell wall]
Reactome.org reaction link: R-HSA-1222325
======
Reaction input - small molecules:
desferrimycobactin T
Reaction output - small molecules:
carboxymycobactin
Reactome.org link: R-HSA-1222325