Reaction: Hydroperoxyl enters the bacterium
- in pathway: ROS and RNS production in phagocytes
Superoxide can enter the bacterium when acidic conditions apply. Together with a proton it forms the uncharged hydroperoxyl radical (OOH·) which is membrane permeable (Nathan & Shiloh 2000, Zahrt & Deretic 2002, Warner & Mizrahi 2006, Spagnolo et al, 2004).
Reaction - small molecule participants:
hydroperoxyl [cytosol]
hydroperoxyl [phagocytic vesicle lumen]
Reactome.org reaction link: R-HSA-1222342
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Reaction input - small molecules:
hydroperoxyl
Reaction output - small molecules:
hydroperoxyl
Reactome.org link: R-HSA-1222342