Reaction: Glutathione scavenges nitrosyl
- in pathway: ROS and RNS production in phagocytes
In the host cell cytosol, glutathione (GSH) scavenges nitrosyl, yielding S-nitrosoglutathione (GSNO). Both GSH and GSNO are effective against Mtb (Venketaraman et al. 2005).
Reaction - small molecule participants:
H+ [cytosol]
GSNO [cytosol]
NO+ [cytosol]
GSH [cytosol]
Reactome.org reaction link: R-HSA-1222384
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Reaction input - small molecules:
oxidonitrogen(1+)
glutathionate(1-)
Reaction output - small molecules:
hydron
S-nitrosoglutathione
Reactome.org link: R-HSA-1222384