Reaction: lpdC dimer reactivates dlaT
- in pathway: Cell redox homeostasis
Peroxiredoxin AhpC gets its reducing equivalents through a cascade of proteins via AhpD, a disulfide reductase, DlaT, a lipoylated disulfide reductase, and, finally, from lpdC, the NADH-dependent dihydrolipoyl reductase. The latter two are also part of the pyruvate dehydrogenase complex (Venugopal et al. 2011).
Reaction - small molecule participants:
NAD+ [cytosol]
H+ [cytosol]
NADH [cytosol]
Reactome.org reaction link: R-HSA-1222412
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Reaction input - small molecules:
hydron
NADH(2-)
Reaction output - small molecules:
NAD(1-)
Reactome.org link: R-HSA-1222412