Reaction: Peroxynitrite is reduced to nitrite by Tpx
- in pathway: Tolerance by Mtb to nitric oxide produced by macrophages
Tpx, like AhpC, is a peroxiredoxin with alkylhydroperoxidase, peroxidase, and peroxynitritase activities. Peroxynitrite is detoxified to nitrite (Jaeger et al. 2006, Rho et al. 2006).
Reaction - small molecule participants:
H2O [cytosol]
Nitrite [cytosol]
Peroxynitrite [cytosol]
Reactome.org reaction link: R-HSA-1222755
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Reaction input - small molecules:
peroxynitrite
Reaction output - small molecules:
water
nitrite
Reactome.org link: R-HSA-1222755