Reaction: Exogenous soluble antigen targeted to more stable early endosome
Within the endosome the receptor and cargo separate and the receptor recycles back to the cell surface. Soluble antigens are targeted into the stable early endosome lumen for efficient cross presentation. Early endosomes are mildly acidic and relatively poor in proteases.
Reaction - small molecule participants:
Exogenous soluble antigen [early endosome lumen]
Reactome.org reaction link: R-HSA-1236940
======
Reaction input - small molecules:
Reaction output - small molecules:
peptide
Reactome.org link: R-HSA-1236940