Reaction: AQP1 tetramer transports CO2 from extracellular region to cytosol
- in pathway: Erythrocytes take up carbon dioxide and release oxygen
Aquaporin-1 (AQP1) passively transports carbon dioxide (CO2) across the plasma membrane according to the concentration gradient (Nakhoul et al. 1998, Blank & Ehmke et al. 2003, Endeward et al. 2006, Musa-Aziz et al. 2009). The pore in AQP1 that conducts CO2 may be distinct from the pore that conducts water.
Reaction - small molecule participants:
CO2 [cytosol]
CO2 [extracellular region]
Reactome.org reaction link: R-HSA-1237042
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Reaction input - small molecules:
carbon dioxide
Reaction output - small molecules:
carbon dioxide
Reactome.org link: R-HSA-1237042