Reaction: Transamination of MOB to methionine
- in pathway: Methionine salvage pathway
In the last step MOB gets transaminated to methionine. The reaction was confirmed in yeast, where several transaminases catalyze it, which appears to be also the case in rat. At the moment, the human enzymes involved are unknown but due to homology to the respective enzyme in the parasite Crithidia fasciculata we feel supported to state that human GOT is probably one of the involved transaminases. (Berger et al, 2001)
Reaction - small molecule participants:
2-Oxoacid [cytosol]
L-Met [cytosol]
L-amino acid [cytosol]
4MTOBUTA [cytosol]
Reactome.org reaction link: R-HSA-1237102
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Reaction input - small molecules:
L-alpha-amino acid zwitterion
4-methylthio-2-oxobutanoate
Reaction output - small molecules:
2-oxo monocarboxylic acid anion
L-methionine zwitterion
Reactome.org link: R-HSA-1237102