Reaction: CNDP2:2Mn2+ dimer hydrolyses CysGly
- in pathway: Glutathione synthesis and recycling
Cytosolic, non-specific peptidase (CNDP2) can hydrolyse cysteinylglycine (CysGly) to release cysteine (L-Cys) and glycine (Gly) (Tuefel et al. 2003). CNDP2 is functional as a homodimer and requires 2 Mn2+ ion per subunit.
Reaction - small molecule participants:
L-Cys [cytosol]
Gly [cytosol]
H2O [cytosol]
CysGly [cytosol]
Reactome.org reaction link: R-HSA-1247910
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Reaction input - small molecules:
water
L-cysteinylglycine zwitterion
Reaction output - small molecules:
L-cysteine zwitterion
glycine zwitterion
Reactome.org link: R-HSA-1247910