Reaction: OPLAH hydrolyses OPRO to L-Glu
- in pathway: Glutathione synthesis and recycling
5-oxoprolinase catalyzes the cleavage of 5-oxoproline to form L-glutamate, coupled to the hydrolysis of ATP to ADP and inorganic phosphate (Chen et al, 1998).
Reaction - small molecule participants:
Pi [cytosol]
L-Glu [cytosol]
ADP [cytosol]
H2O [cytosol]
ATP [cytosol]
OPRO [cytosol]
Reactome.org reaction link: R-HSA-1247935
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Reaction input - small molecules:
water
ATP(4-)
5-oxo-L-prolinate
Reaction output - small molecules:
hydrogenphosphate
L-glutamate(1-)
ADP(3-)
Reactome.org link: R-HSA-1247935