Reaction: PLCG1 phosphorylation by p-EGFR:p-ERBB2
- in pathway: PLCG1 events in ERBB2 signaling
Phospholipase C gamma 1 (PLCG1) is phosphorylated by phosphorylated EGFR:ERBB2 heterodimer (Fazioli et al. 1991, Cohen et al. 1996).
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-1251922
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-1251922