Reaction: 2-acyl LPG is acylated to PG by CRLS1 (IM)
- in pathway: Acyl chain remodelling of PG
At the inner mitochondrial membrane (IM), cardiolipin synthase (CRLS1) acylates 2-acyl lysophosphatidylglycerol (LPG) to form phosphatidylglycerol (PG) (Nie et al. 2010).
Reaction - small molecule participants:
CoA-SH [mitochondrial matrix]
PG [mitochondrial inner membrane]
2-acyl LPG [mitochondrial inner membrane]
acyl-CoA [mitochondrial matrix]
Reactome.org reaction link: R-HSA-1482546
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Reaction input - small molecules:
2-acyl-sn-glycero-3-phosphoglycerol
acyl-CoA
Reaction output - small molecules:
coenzyme A(4-)
1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-)
Reactome.org link: R-HSA-1482546