Reaction: 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C
- in pathway: Hydrolysis of LPE
At the endoplasmic reticulum (ER) membrane, membrane-bound cytosolic phospholipase A2 gamma (PLA2G4C) hydrolyzes 1-acyl lysophosphatidylethanolamine (LPE) to produce glycerophosphoethanolamine (GPETA) (Yamashita et al. 2005, Yamashita et al. 2009).
Reaction - small molecule participants:
LCFA(-) [endoplasmic reticulum membrane]
GPETA [cytosol]
H2O [cytosol]
1-acyl LPE [endoplasmic reticulum membrane]
Reactome.org reaction link: R-HSA-1482571
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Reaction input - small molecules:
water
1-acyl-sn-glycero-3-phosphoethanolamine
Reaction output - small molecules:
long-chain fatty acid anion
sn-glycero-3-phosphoethanolamine
Reactome.org link: R-HSA-1482571