Reaction: 2-MAG and DAG are transacylated to TAG by PNPLA2/3
- in pathway: Acyl chain remodeling of DAG and TAG
At the endoplasmic reticulum (ER) membrane, a 2-monoacylglycerol (2-MAG) molecule and a diacylglycerol (DAG) molecule are transacylated by patatin-like phospholipase domain-containing proteins 2/3 (PNPLA2/3). This forms triacylglycerol (TAG) and glycerol (Jenkins et al. 2004).
Reaction - small molecule participants:
Glycerol [cytosol]
TAG [endoplasmic reticulum membrane]
2-MAG [endoplasmic reticulum membrane]
DAG [endoplasmic reticulum membrane]
Reactome.org reaction link: R-HSA-1482647
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Reaction input - small molecules:
2-monoglyceride
1,2-diacyl-sn-glycerol
Reaction output - small molecules:
glycerol
triglyceride
Reactome.org link: R-HSA-1482647