Reaction: 2-MAG is transacylated to DAG by PNPLA2/3
- in pathway: Acyl chain remodeling of DAG and TAG
At the endoplasmic reticulum (ER) membrane, two 2-monoacylglycerol (2-MAG) molecules are transacylated by patatin-like phospholipase domain-containing proteins 2/3 (PNPLA2/3) to form diacylglycerol (DAG) and glycerol (Jenkins et al. 2004).
Reaction - small molecule participants:
Glycerol [cytosol]
DAG [endoplasmic reticulum membrane]
2-MAG [endoplasmic reticulum membrane]
Reactome.org reaction link: R-HSA-1482654
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Reaction input - small molecules:
2-monoglyceride
Reaction output - small molecules:
glycerol
1,2-diacyl-sn-glycerol
Reactome.org link: R-HSA-1482654