Reaction: G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM)
- in pathway: Synthesis of PA
Glycerol-3-phosphate (G3P) is acylated to 1-acyl lysophosphatidic acid (LPA) by the enzymes glycerol-3-phosphate acyltransferase 1 (GPAT, also known as GPAM) and glycerol-3-phosphate acyltransferase 2 (GPAT2), at the outer mitochondrial (OM) membrane (Shindou & Shimizu 2009, Chen et al. 2008, Takeuchi & Reue 2009).
Reaction - small molecule participants:
CoA-SH [cytosol]
1-acyl LPA [mitochondrial outer membrane]
acyl-CoA [cytosol]
G3P [cytosol]
Reactome.org reaction link: R-HSA-1482695
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Reaction input - small molecules:
acyl-CoA
sn-glycerol 3-phosphate(2-)
Reaction output - small molecules:
coenzyme A(4-)
1-acyl-sn-glycerol 3-phosphate
Reactome.org link: R-HSA-1482695