Reaction: 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C
- in pathway: Hydrolysis of LPC
At the endoplasmic reticulum (ER) membrane, 1-acyl lysophosphatidylcholine (LPC) is hydrolyzed to glycerophosphocholine (GPCho) by membrane-bound cytosolic phospholipase A2 gamma (PLA2G4C) (Yamashita et al. 2005, Ghomashchi et al. 2010, Yamashita et al. 2009).
Reaction - small molecule participants:
GPCho [cytosol]
LCFA(-) [endoplasmic reticulum membrane]
H2O [cytosol]
1-acyl LPC [endoplasmic reticulum membrane]
Reactome.org reaction link: R-HSA-1482696
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Reaction input - small molecules:
water
1-O-acyl-sn-glycero-3-phosphocholine(1+)
Reaction output - small molecules:
choline alfoscerate
long-chain fatty acid anion
Reactome.org link: R-HSA-1482696