Reaction: MLCL is acylated to CL by LCLAT1 (ER)
- in pathway: Acyl chain remodeling of CL
At the endoplasmic reticulum (ER) membrane, lysocardiolipin acyltransferase 1 (LCLAT1) aka ALCAT1 acylates monolysocardiolipin (MLCL) to cardiolipin (CL) (Cao et al. 2004, Zhao et al. 2009).
Reaction - small molecule participants:
CL [endoplasmic reticulum membrane]
CoA-SH [cytosol]
acyl-CoA [cytosol]
MLCL [endoplasmic reticulum membrane]
Reactome.org reaction link: R-HSA-1482861
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Reaction input - small molecules:
acyl-CoA
2-monolysocardiolipin
Reaction output - small molecules:
cardiolipin
coenzyme A(4-)
Reactome.org link: R-HSA-1482861