Reaction: CDP-DAG is converted to PGP by PGS1
- in pathway: Synthesis of PG
At the inner mitochondrial (IM) membrane, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (PGS1) converts cytidine diphosphate-diacylglycerol (CDP-DAG) and glycerol-3-phosphate (G3P) to phosphatidylglycerophosphate (PGP) and cytidine monophosphate (CMP). This event is inferred from rats. The enzyme PGS1 has been characterized in humans (Ota et al. 2004).
Reaction - small molecule participants:
PGP [mitochondrial inner membrane]
CMP [mitochondrial matrix]
G3P [mitochondrial matrix]
CDP-DAG [mitochondrial inner membrane]
Reactome.org reaction link: R-HSA-1482939
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Reaction input - small molecules:
sn-glycerol 3-phosphate(2-)
CDP-diacylglycerol(2-)
Reaction output - small molecules:
1-(3-sn-phosphatidyl)-sn-glycerol 3-phosphate(3-)
cytidine 5'-monophosphate(2-)
Reactome.org link: R-HSA-1482939