Reaction: DHAP is converted to 1-acyl GO3P by GNPAT
- in pathway: Synthesis of PA
Dihydroxyacetone phosphate (DHAP) is converted to 1-acyl glycerone 3-phosphate (GO3P) by the enzyme dihydroxyacetone phosphate acyltransferase (GNPAT) (de Vet et al. 1999, Ofman et al. 1994). This reaction step links Glycerolipid metabolism to Ether lipid metabolism.
Reaction - small molecule participants:
GO3P [cytosol]
CoA-SH [cytosol]
acyl-CoA [cytosol]
DHAP [cytosol]
Reactome.org reaction link: R-HSA-1483002
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Reaction input - small molecules:
acyl-CoA
glycerone phosphate(2-)
Reaction output - small molecules:
1-alkylglycerone 3-phosphate(2-)
coenzyme A(4-)
Reactome.org link: R-HSA-1483002