Reaction: Cho is phosphorylated to PCho by CHK dimer
- in pathway: Synthesis of PC
In the cytosol, choline kinase alpha subunit (CHKA) homodimer, choline kinase beta subunit (CHKB) dimer, or CHKA:CHKB heterodimer phosphorylates choline (Cho) to produce phosphocholine (PCho) (Malito et al. 2006, Gallego-Ortega et al. 2009).
Reaction - small molecule participants:
ADP [cytosol]
PCho [cytosol]
Cho [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-1483004
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Reaction input - small molecules:
choline
ATP(4-)
Reaction output - small molecules:
ADP(3-)
phosphocholines
Reactome.org link: R-HSA-1483004