Reaction: GPCho is hydrolyzed to Cho and G3P by GPCPD1
- in pathway: Hydrolysis of LPC
In the cytosol, glycerophosphocholine phosphodiesterase (GPCPD1, also known as GDE5) hydrolyzes glycerophosphocholine (GPCho) to produce choline (Cho) and glycerol-3-phosphate (G3P). This event has been inferred from mice. GPCPD1 has also been characterized in humans (Ota et al. 2004).
Reaction - small molecule participants:
Cho [cytosol]
G3P [cytosol]
H2O [cytosol]
GPCho [cytosol]
Reactome.org reaction link: R-HSA-1483116
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Reaction input - small molecules:
water
choline alfoscerate
Reaction output - small molecules:
choline
sn-glycerol 3-phosphate(2-)
Reactome.org link: R-HSA-1483116