Reaction: PETA and CTP are condensed to CDP-ETA by PCY2
- in pathway: Synthesis of PE
At the endoplasmic reticulum (ER) membrane, active membrane-bound ethanolamine-phosphate cytidylyltransferase (PCY2) dimer condenses phosphoethanolamine (PETA) and cytidine triphosphate (CTP) to produce CDP-ethanolamine (CDP-ETA) (Zhu et al. 2008, Nakashima et al. 1997).
Reaction - small molecule participants:
PPi [cytosol]
CDP-ETA [cytosol]
PETA [cytosol]
CTP [cytosol]
Reactome.org reaction link: R-HSA-1483190
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Reaction input - small molecules:
O-phosphoethanolamine
CTP(4-)
Reaction output - small molecules:
diphosphate(3-)
CDP-ethanolamine(1-)
Reactome.org link: R-HSA-1483190