Reaction: PTPMT1 dephosphorylates PGP to PG
- in pathway: Synthesis of PG
At the inner mitochondrial (IM) membrane, PTPMT1 (phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1) catalyzes the dephosphorylation of phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). The biochemical properties of human PTPMT1 have not been determined; this reaction is inferred from the one catalyzed by the homologous mouse protein (Zhang et al. 2011).
Reaction - small molecule participants:
Pi [mitochondrial matrix]
PG [mitochondrial inner membrane]
PGP [mitochondrial inner membrane]
H2O [mitochondrial matrix]
Reactome.org reaction link: R-HSA-1483197
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Reaction input - small molecules:
1-(3-sn-phosphatidyl)-sn-glycerol 3-phosphate(3-)
water
Reaction output - small molecules:
hydrogenphosphate
1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-)
Reactome.org link: R-HSA-1483197