Reaction: PA is dephosphorylated to DAG by LPIN
- in pathway: Synthesis of PC
At the endoplasmic reticulum (ER) membrane, phosphatidate phosphatase 1-3 (LPIN) dephosphorylates phosphatidic acid (PA) to form diacylglycerol (DAG) (Grimsey et al. 2008, Donkor et al. 2007).
Reaction - small molecule participants:
Pi [cytosol]
DAG [endoplasmic reticulum membrane]
H2O [cytosol]
PA [endoplasmic reticulum membrane]
Pi [cytosol]
DAG [endoplasmic reticulum membrane]
H2O [cytosol]
PA [endoplasmic reticulum membrane]
Reactome.org reaction link: R-HSA-1483203
======
Reaction input - small molecules:
water
phosphatidate(2-)
water
phosphatidate(2-)
Reaction output - small molecules:
hydrogenphosphate
1,2-diacyl-sn-glycerol
hydrogenphosphate
1,2-diacyl-sn-glycerol
Reactome.org link: R-HSA-1483203