Reaction: PG transports from the ER membrane to the late endosome membrane
- in pathway: Synthesis of BMP
Lysobisphosphatidic acid, also known as bis(monoacylglycerol) hydrogen phosphate (BMP), is enriched in late endosomes and not found in the endoplasmic reticulum (ER) or mitochondria where phosphatidylglycerol (PG) is synthesised. Late endosomes form membrane contact sites with the ER, providing a means for PG to enter the late endosome and be converted to BMP (Levine 2004, Eden et al. 2010, Kobayashi et al. 1998, Hullin-Matsuda et al. 2007, Kobayashi et al. 1999).
Reaction - small molecule participants:
PG [late endosome membrane]
PG [endoplasmic reticulum membrane]
Reactome.org reaction link: R-HSA-1483218
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Reaction input - small molecules:
1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-)
Reaction output - small molecules:
1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-)
Reactome.org link: R-HSA-1483218