Reaction: ETA is phosphorylated to PETA by CHK/ETNK
- in pathway: Synthesis of PE
In the cytosol, ethanolamine (ETA) is phosphorylated to phosphoethanolamine (PETA) by choline kinase (CHK) dimer or by ethanolamine kinase 1/2 (ETNK1/2) (Lykidis et al. 2001, Gallego-Ortega et al. 2009). CHK dimer consists of either choline kinase alpha subunit (CHKA) or beta subunit (CHKB) homodimer, or of CHKA:CHKB heterodimer.
Reaction - small molecule participants:
ADP [cytosol]
PETA [cytosol]
ATP [cytosol]
ETA [cytosol]
Reactome.org reaction link: R-HSA-1483222
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Reaction input - small molecules:
ATP(4-)
ethanolamine
Reaction output - small molecules:
ADP(3-)
O-phosphoethanolamine
Reactome.org link: R-HSA-1483222