Reaction: BfrA stores iron
- in pathway: Mtb iron assimilation by chelation
Mtb bacterioferritin BfrA oxidises Fe2+ to Fe3+, migrates them to its centre, and collects thousands of them as FeO(OH) in the central mineral core from which they can be later remobilised (Reddy et al. 2012).
Reaction - small molecule participants:
H2O [cytosol]
Fe3+ [cytosol]
H+ [cytosol]
Fe2+ [cytosol]
O2 [cytosol]
Reactome.org reaction link: R-HSA-1562604
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Reaction input - small molecules:
hydron
iron(2+)
dioxygen
Reaction output - small molecules:
water
iron(3+)
Reactome.org link: R-HSA-1562604