Reaction: Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH)
- in pathway: Iron uptake and transport
Ferritin oxidises Fe(2+) ions to Fe(3+), migrates them to its centre, and collects thousands of them as ferric hydroxide (Fe(3+)O(OH)) in the central mineral core from which they can be later remobilised (Harrison & Arrosio 1996).
Reaction - small molecule participants:
Fe(3+)O(OH) [cytosol]
H+ [cytosol]
Fe2+ [cytosol]
O2 [cytosol]
Reactome.org reaction link: R-HSA-1562626
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Reaction input - small molecules:
hydron
iron(2+)
dioxygen
Reaction output - small molecules:
iron(III) oxide-hydroxide(1-)
Reactome.org link: R-HSA-1562626