Reaction: PC is hydrolyzed to 1-acyl LPC by PLB1
- in pathway: Acyl chain remodelling of PC
At the plasma membrane, phosphatidylcholine (PC) is hydrolyzed, removing one of its acyl groups, to 1-acyl lysophosphatidylcholine (LPC) by membrane-associated phospholipase B1 (PLB1) (Maury et al. 2002, Gassama-Diagne et al. 1992).
Reaction - small molecule participants:
1-acyl LPC [plasma membrane]
LCFA(-) [plasma membrane]
H2O [extracellular region]
PC [plasma membrane]
Reactome.org reaction link: R-HSA-1602399
======
Reaction input - small molecules:
water
1,2-diacyl-sn-glycero-3-phosphocholine
Reaction output - small molecules:
1-O-acyl-sn-glycero-3-phosphocholine(1+)
long-chain fatty acid anion
Reactome.org link: R-HSA-1602399