Reaction: Persulfide sulfur is transferred onto sulfite
- in pathway: Sulfide oxidation to sulfate
The main reaction catalyzed by rhodanase is not the name-giving detoxification of cyanide to thiocyanate, but the transfer of a sulfur atom from SQR-S-SH onto sulfite yielding thiosulfate during sulfide oxidation. The activity of human rhodanase was inferred from the rat orthologue by Hildebrandt & Grieshaber, 2008.
Reaction - small molecule participants:
S2O3(2-) [mitochondrial matrix]
sulfite(2-) [mitochondrial matrix]
Reactome.org reaction link: R-HSA-1614618
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Reaction input - small molecules:
sulfite
Reaction output - small molecules:
trioxidosulfanidosulfate(1-)
Reactome.org link: R-HSA-1614618