Reaction: p-T309,S474-AKT2:PIP3 phosphorylates PDE3B
- in pathway: PDE3B signalling
Based on work done in mouse with AKT1, AKT2 is predicted to phosphorylate PDE3B downstream of insulin signaling (Wijknader et al, 1998; Kitamura et al, 1999; Ahmad et al, 2000; reviewed in Degerman et al, 2011).
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-162363
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-162363