Reaction: p-S295-PDE3B hydrolyses cAMP to AMP
- in pathway: PDE3B signalling
PDE3B hydrolyzes cAMP to AMP downstream of insulin signaling to regulate energy homeostasis (Marganiello et al, 1995; Degerman et al, 1997; Degerman et al, 2011; DiPilato et al, 2015).
Reaction - small molecule participants:
AMP [cytosol]
H2O [cytosol]
cAMP [cytosol]
Reactome.org reaction link: R-HSA-162425
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Reaction input - small molecules:
water
3',5'-cyclic AMP(1-)
Reaction output - small molecules:
adenosine 5'-monophosphate(2-)
Reactome.org link: R-HSA-162425