Reaction: ULK1 phosphorylates AMBRA1:BECN1 complex
- in pathway: Macroautophagy
Upon autophagy induction, ULK1 phosphorylates AMBRA1, which leads to the release of the Beclin-1 complex from the dynein motor complex (Di Bartolomeo et al. 2010).
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-1632857
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-1632857