Reaction: diacylglycerol + H2O -> 2-acylglycerol + fatty acid
- in pathway: Triglyceride catabolism
Rat HSL catalyzes the hydrolysis of diacylglycerol to yield 2-acylglycerol + fatty acid (Fredrikson and Belfrage 1983). The human event has not been studied in detail and is inferred from the rat one.
Reaction - small molecule participants:
2-acylglycerol [lipid droplet]
LCFA(-) [cytosol]
H2O [cytosol]
DAG [lipid droplet]
Reactome.org reaction link: R-HSA-163402
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Reaction input - small molecules:
water
1,2-diacyl-sn-glycerol
Reaction output - small molecules:
2-monoglyceride
long-chain fatty acid anion
Reactome.org link: R-HSA-163402