Reaction: Unknown carnitine exporter transports CAR from the cytosol to the extracellular space
- in pathway: Carnitine synthesis
Studies of carnitine (CAR) export from intact rat liver indicate that this process is mediated by a specific, saturable transporter molecule (Sandor et al. 1985). The transporter that mediates this process in human tissues has not been identified, but its properties are distinct from those of SLC22A5 / OCTN2, the major transport protein responsible for carnitine uptake (Tamai et al. 1998; Wu et al. 1999). Indeed, as noted by Vaz & Wanders (2002), export of carnitine and its metabolites is probably mediated by another transport system, or possibly by passive diffusion.
Reaction - small molecule participants:
CAR [extracellular region]
CAR [cytosol]
Reactome.org reaction link: R-HSA-164967
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Reaction input - small molecules:
carnitine
Reaction output - small molecules:
carnitine
Reactome.org link: R-HSA-164967