Reaction: PXKLP-K305-CSAD decarboxylates 3-sulfinoalanine to hypotaurine
- in pathway: Degradation of cysteine and homocysteine
Cysteine sulfinic acid decarboxylase (CSAD) mediates the decarboxylase of 3-sulfinoalanine to produce hypotuarine. CSAD functions as a homodimer and requires pyridoxal phosphate as a cofactor. Purification, characterisation and activity of CSAD has been determined from rat liver (Guion-Rain et al. 1975).
Reaction - small molecule participants:
HTAU [cytosol]
CO2 [cytosol]
3-Sulfinoalanine [cytosol]
Reactome.org reaction link: R-HSA-1655443
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Reaction input - small molecules:
3-sulfino-L-alanine(1-)
Reaction output - small molecules:
hypotaurine zwitterion
carbon dioxide
Reactome.org link: R-HSA-1655443