Reaction: PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane
- in pathway: Synthesis of PIPs at the plasma membrane
At the plasma membrane, phosphatidylinositol-4-phosphate 5-kinase type-1 alpha (PIP5K1A) and beta (PIP5K1B) phosphorylate phosphatidylinositol (PI) to produce phosphatidylinositol 5-phosphate (PI5P) (Tolias et al. 1998).
Reaction - small molecule participants:
PI5P [plasma membrane]
ADP [cytosol]
ATP [cytosol]
PI [plasma membrane]
Reactome.org reaction link: R-HSA-1675810
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Reaction input - small molecules:
ATP(4-)
1-phosphatidyl-1D-myo-inositol(1-)
Reaction output - small molecules:
1-phosphatidyl-1D-myo-inositol 5-phosphate(3-)
ADP(3-)
Reactome.org link: R-HSA-1675810