Reaction: Presence of PI(3,5)P2 stimulates the maturation of the early endosome into the late endosome
- in pathway: PIPs transport between early and late endosome membranes
The presence of phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) in the early endosome membrane stimulates the vesicle maturation into the late endosome (Cabezas et al. 2006, Ikonomov et al. 2006, Ikonomov et al. 2001).
Reaction - small molecule participants:
PI(3,5)P2 [late endosome membrane]
PI(3,5)P2 [early endosome membrane]
Reactome.org reaction link: R-HSA-1676041
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Reaction input - small molecules:
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate(5-)
Reaction output - small molecules:
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate(5-)
Reactome.org link: R-HSA-1676041