Reaction: Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes
- in pathway: Cyclin A/B1/B2 associated events during G2/M transition
The human Wee1 kinase phosphorylates Cdc2 on tyrosine 15 inactivating the cyclin:CDK complex (Watanabe et al., 1995).
Reaction - small molecule participants:
ADP [nucleoplasm]
ATP [nucleoplasm]
Reactome.org reaction link: R-HSA-170156
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-170156