Reaction: Dephosphorylation of phospho-Cdh1

- in pathway: Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Phosphorylation by mitotic kinases is believed to alter the conformation of Cdh1 preventing it from associating with the APC/C. Cdc14 is thought to contribute to the dephosphorylation of Cdh1 in late mitosis. Dephosphorylated Cdh1 then associates with and activates the APC/C.
Reaction - small molecule participants:
PPi [cytosol]
H2O [cytosol]
Reactome.org reaction link: R-HSA-174124

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Reaction input - small molecules:
water
ChEBI:15377
Reaction output - small molecules:
diphosphate(3-)
ChEBI:33019
Reactome.org link: R-HSA-174124