Reaction: SULTs transfer (SO4)2- group to 27HCHOL
- in pathway: Cytosolic sulfonation of small molecules
The sulfonation of 27-hydroxycholesterol (27HCHOL) is catalyzed by both the a and b isoforms of SULT2B1 (Javitt et al. 2001).
Reaction - small molecule participants:
27HCHOL3S [cytosol]
PAP [cytosol]
27HCHOL [endoplasmic reticulum membrane]
PAPS [cytosol]
Reactome.org reaction link: R-HSA-176494
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Reaction input - small molecules:
26-hydroxycholesterol
3'-phosphonato-5'-adenylyl sulfate(4-)
Reaction output - small molecules:
26-hydroxycholesterol 3-sulfate
adenosine 3',5'-bismonophosphate(4-)
Reactome.org link: R-HSA-176494