Reaction: SULTs transfer (SO4)2- group to PREG
- in pathway: Cytosolic sulfonation of small molecules
The sulfonation of pregnenolone (PREG) is catalyzed by both the a and b isoforms of SULT2B1, although the a isoform is more active in assays in vitro (Fuda et al. 2002; Meloche and Falany 2001).
Reaction - small molecule participants:
PREGS [cytosol]
PAP [cytosol]
PREG [cytosol]
PAPS [cytosol]
Reactome.org reaction link: R-HSA-176517
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Reaction input - small molecules:
pregnenolone
3'-phosphonato-5'-adenylyl sulfate(4-)
Reaction output - small molecules:
pregnenolone sulfate
adenosine 3',5'-bismonophosphate(4-)
Reactome.org link: R-HSA-176517