Reaction: PKA phosphorylates PDE4B
- in pathway: DARPP-32 events
The phosphorylation of the phosphodiesterase increases its activity, forming a negative feedback loop of the cAMP signal.
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-177284
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-177284